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Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects
Alzheimer's disease (AD) is a neurodegenerative disease pathologically characterized by amyloid plaques and neurofibrillary tangles in the brain. Before these hallmark features appear, signs of axonal transport defects develop, though the initiating events are not clear. Enhanced amyloidogenic...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471392/ https://ncbi.nlm.nih.gov/pubmed/22843498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds297 |
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