UV Irradiation Accelerates Amyloid Precursor Protein (APP) Processing and Disrupts APP Axonal Transport

Overexpression and/or abnormal cleavage of amyloid precursor protein (APP) are linked to Alzheimer's disease (AD) development and progression. However, the molecular mechanisms regulating cellular levels of APP or its processing, and the physiological and pathological consequences of altered pr...

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書誌詳細
主要な著者: Almenar-Queralt, Angels, Falzone, Tomas L., Shen, Zhouxin, Lillo, Concepcion, Killian, Rhiannon L., Arreola, Angela S., Niederst, Emily D., Ng, Kheng S., Kim, Sonia N., Briggs, Steven P., Williams, David S., Goldstein, Lawrence S.B.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2014
主題:
Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935090/
https://ncbi.nlm.nih.gov/pubmed/24573290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1503-13.2014
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