UV Irradiation Accelerates Amyloid Precursor Protein (APP) Processing and Disrupts APP Axonal Transport

Overexpression and/or abnormal cleavage of amyloid precursor protein (APP) are linked to Alzheimer's disease (AD) development and progression. However, the molecular mechanisms regulating cellular levels of APP or its processing, and the physiological and pathological consequences of altered pr...

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Detalhes bibliográficos
Main Authors: Almenar-Queralt, Angels, Falzone, Tomas L., Shen, Zhouxin, Lillo, Concepcion, Killian, Rhiannon L., Arreola, Angela S., Niederst, Emily D., Ng, Kheng S., Kim, Sonia N., Briggs, Steven P., Williams, David S., Goldstein, Lawrence S.B.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935090/
https://ncbi.nlm.nih.gov/pubmed/24573290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1503-13.2014
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