Amyloid precursor protein-induced axonopathies are independent of amyloid-β peptides

Overexpression of amyloid precursor protein (APP), as well as mutations in the APP and presenilin genes, causes rare forms of Alzheimer’s disease (AD). These genetic changes have been proposed to cause AD by elevating levels of amyloid-β peptides (Aβ), which are thought to be neurotoxic. Since overe...

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Main Authors: Stokin, Gorazd B., Almenar-Queralt, Angels, Gunawardena, Shermali, Rodrigues, Elizabeth M., Falzone, Tomás, Kim, Jungsu, Lillo, Concepción, Mount, Stephanie L., Roberts, Elizabeth A., McGowan, Eileen, Williams, David S., Goldstein, Lawrence S.B.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2008
נושאים:
Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722897/
https://ncbi.nlm.nih.gov/pubmed/18694898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn240
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