Amyloid precursor protein-induced axonopathies are independent of amyloid-β peptides

Overexpression of amyloid precursor protein (APP), as well as mutations in the APP and presenilin genes, causes rare forms of Alzheimer’s disease (AD). These genetic changes have been proposed to cause AD by elevating levels of amyloid-β peptides (Aβ), which are thought to be neurotoxic. Since overe...

Πλήρης περιγραφή

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Κύριοι συγγραφείς: Stokin, Gorazd B., Almenar-Queralt, Angels, Gunawardena, Shermali, Rodrigues, Elizabeth M., Falzone, Tomás, Kim, Jungsu, Lillo, Concepción, Mount, Stephanie L., Roberts, Elizabeth A., McGowan, Eileen, Williams, David S., Goldstein, Lawrence S.B.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2008
Θέματα:
Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722897/
https://ncbi.nlm.nih.gov/pubmed/18694898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn240
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