Caricamento...

Fragment-Based Screening of the Bromodomain of ATAD2

[Image: see text] Cellular and genetic evidence suggest that inhibition of ATAD2 could be a useful strategy to treat several types of cancer. To discover small-molecule inhibitors of the bromodomain of ATAD2, we used a fragment-based approach. Fragment hits were identified using NMR spectroscopy, an...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Med Chem
Autori principali: Harner, Mary J., Chauder, Brian A., Phan, Jason, Fesik, Stephen W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255743/
https://ncbi.nlm.nih.gov/pubmed/25314628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm501035j
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !