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Fragment-Based Drug Discovery Using NMR Spectroscopy

Nuclear magnetic resonance (NMR) spectroscopy has evolved into a powerful tool for fragment-based drug discovery over the last two decades. While NMR has been traditionally used to elucidate the three-dimensional structures and dynamics of biomacromolecules and their interactions, it can also be a v...

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Detalhes bibliográficos
Main Authors: Harner, Mary J., Frank, Andreas O., Fesik, Stephen W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699969/
https://ncbi.nlm.nih.gov/pubmed/23686385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-013-9740-z
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