A carregar...
Crystallographic Fragment Based Drug Discovery: Use of a Brominated Fragment Library Targeting HIV Protease
A library of 68 brominated fragments was screened against a new crystal form of inhibited HIV-1 protease in order to probe surface sites in soaking experiments. Often fragments are weak binders with partial occupancy, resulting in weak, difficult-to-fit electron density. The use of a brominated frag...
Na minha lista:
| Main Authors: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3898673/ https://ncbi.nlm.nih.gov/pubmed/23998903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12227 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|