Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC

MYC is an oncoprotein transcription factor that is overexpressed in the majority of malignancies. The oncogenic potential of MYC stems from its ability to bind regulatory sequences in thousands of target genes, which depends on interaction of MYC with its obligate partner, MAX. Here, we show that br...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell
Egile Nagusiak: Thomas, Lance R., Wang, Qingguo, Grieb, Brian C., Phan, Jason, Foshage, Audra M., Sun, Qi, Olejniczak, Edward T., Clark, Travis, Dey, Soumyadeep, Lorey, Shelly, Alicie, Bethany, Howard, Gregory C., Cawthon, Bryan, Ess, Kevin C., Eischen, Christine M., Zhao, Zhongming, Fesik, Stephen W., Tansey, William P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427524/
https://ncbi.nlm.nih.gov/pubmed/25818646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.02.028
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak