Crystal structure of the Yersinia type III secretion protein YscE

le Phan, Jason, Austin, Brian P., Waugh, David S.
Foilsithe 2005

Erosion of Embolization Coils into the Renal Collecting System Mimicking Stone

le Phan, Jason, Lall, Chandana, Moskowitz, Ross, Clayman, Ralph, Landman, Jaime
Foilsithe 2012

Fragment-Based Screening of the Bromodomain of ATAD2

le Harner, Mary J., Chauder, Brian A., Phan, Jason, Fesik, Stephen W.
Foilsithe in J Med Chem (2014)

Physical Therapy for Gait, Balance, and Cognition in Individuals with Cognitive Impairment: A Retrospective Analysis

le Longhurst, Jason, Phan, Jason, Chen, Elbert, Jackson, Steven, Landers, Merrill R.
Foilsithe in Rehabil Res Pract (2020)

Structure-based Design of High Affinity Peptides Inhibiting the Interaction of p53 with MDM2 and MDMX

le Phan, Jason, Li, Zhenyu, Kasprzak, Agnieszka, Li, Baozong, Sebti, Said, Guida, Wayne, Schönbrunn, Ernst, Chen, Jiandong
Foilsithe 2010

A method for the second-site screening of K-Ras in the presence of a covalently attached first-site ligand

le Sun, Qi, Phan, Jason, Friberg, Anders R., Camper, DeMarco V., Olejniczak, Edward T., Fesik, Stephen W.
Foilsithe in J Biomol NMR (2014)

Heterologous desensitization of cardiac β-adrenergic signal via hormone-induced βAR/arrestin/PDE4 complexes

le Shi, Qian, Li, Minghui, Mika, Delphine, Fu, Qin, Kim, Sungjin, Phan, Jason, Shen, Ao, Vandecasteele, Gregoire, Xiang, Yang K.
Foilsithe in Cardiovasc Res (2017)

Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation

le Sun, Qi, Burke, Jason P., Phan, Jason, Burns, Michael C., Olejniczak, Edward T., Waterson, Alex G., Lee, Taekyu, Rossanese, Olivia W., Fesik, Stephen W.
Foilsithe 2012

Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange

le Burns, Michael C., Sun, Qi, Daniels, R. Nathan, Camper, DeMarco, Kennedy, J. Phillip, Phan, Jason, Olejniczak, Edward T., Lee, Taekyu, Waterson, Alex G., Rossanese, Olivia W., Fesik, Stephen W.
Foilsithe 2014

High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling

le Burns, Michael C., Howes, Jennifer E., Sun, Qi, Little, Andrew J., Camper, DeMarco V., Abbott, Jason R., Phan, Jason, Lee, Taekyu, Waterson, Alex G., Rossanese, Olivia W., Fesik, Stephen W.
Foilsithe in Anal Biochem (2018)

Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS

le Abbott, Jason R., Patel, Pratiq A., Howes, Jennifer E., Akan, Denis T., Kennedy, J. Phillip, Burns, Michael C., Browning, Carrie F., Sun, Qi, Rossanese, Olivia W., Phan, Jason, Waterson, Alex G., Fesik, Stephen W.
Foilsithe in ACS Med Chem Lett (2018)

Discovery of WD Repeat-Containing Protein 5 (WDR5)-MYC inhibitors using fragment-based methods and structure-based design

le Chacón Simon, Selena, Wang, Feng, Thomas, Lance R., Phan, Jason, Zhao, Bin, Olejniczak, Edward T., Macdonald, Jonathan D., Shaw, J. Grace, Schlund, Caden, Payne, William, Creighton, Joy, Stauffer, Shaun R., Waterson, Alex G., Tansey, William P., Fesik, Stephen W.
Foilsithe in J Med Chem (2020)

Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC

le Thomas, Lance R., Wang, Qingguo, Grieb, Brian C., Phan, Jason, Foshage, Audra M., Sun, Qi, Olejniczak, Edward T., Clark, Travis, Dey, Soumyadeep, Lorey, Shelly, Alicie, Bethany, Howard, Gregory C., Cawthon, Bryan, Ess, Kevin C., Eischen, Christine M., Zhao, Zhongming, Fesik, Stephen W., Tansey, William P.
Foilsithe in Mol Cell (2015)

Discovery of Potent 2-Aryl-6,7-Dihydro-5H-Pyrrolo[1,2-a]imidazoles as WDR5 WIN-site Inhibitors Using Fragment-Based Methods and Structure-Based Design

le Wang, Feng, Jeon, Kyu Ok, Salovich, James M., Macdonald, Jonathan D., Alvarado, Joseph, Gogliotti, Rocco D., Phan, Jason, Olejniczak, Edward T., Sun, Qi, Wang, Shidong, Camper, DeMarco, Yuh, Joannes P., Shaw, J. Grace, Sai, Jiqing, Rossanese, Olivia W., Tansey, William P., Stauffer, Shaun R., Fesik, Stephen W.
Foilsithe in J Med Chem (2018)

Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS

le Hodges, Timothy R., Abbott, Jason R., Little, Andrew J., Sarkar, Dhruba, Salovich, James M., Howes, Jennifer E., Akan, Denis T., Sai, Jiqing, Arnold, Allison L., Browning, Carrie, Burns, Michael C., Sobolik, Tammy, Sun, Qi, Beesetty, Yugandhar, Coker, Jesse A., Scharn, Dirk, Stadtmueller, Heinz, Rossanese, Olivia W., Phan, Jason, Waterson, Alex G., McConnell, Darryl B., Fesik, Stephen W.
Foilsithe in J Med Chem (2018)

Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5 (WDR5)–MYC Protein–Protein Interaction

le Macdonald, Jonathan D., Simon, Selena Chacón, Han, Changho, Wang, Feng, Shaw, J. Grace, Howes, Jennifer E., Sai, Jiqing, Yuh, Joannes P., Camper, Demarco, Alicie, Bethany M., Alvarado, Joseph, Nikhar, Sameer, Payne, William, Aho, Erin R., Bauer, Joshua A., Zhao, Bin, Phan, Jason, Thomas, Lance R., Rossanese, Olivia W., Tansey, William P., Waterson, Alex G., Stauffer, Shaun R., Fesik, Stephen W.
Foilsithe in J Med Chem (2019)

Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity

le Aho, Erin R., Wang, Jing, Gogliotti, Rocco D., Howard, Gregory C., Phan, Jason, Acharya, Pankaj, Macdonald, Jonathan D., Cheng, Ken, Lorey, Shelly L., Lu, Bin, Wenzel, Sabine, Foshage, Audra M., Alvarado, Joseph, Wang, Feng, Shaw, J. Grace, Zhao, Bin, Weissmiller, April M., Thomas, Lance R., Vakoc, Christopher R., Hall, Matthew D., Hiebert, Scott W., Liu, Qi, Stauffer, Shaun R., Fesik, Stephen W., Tansey, William P.
Foilsithe in Cell Rep (2019)

Drugging an undruggable pocket on KRAS

le Kessler, Dirk, Gmachl, Michael, Mantoulidis, Andreas, Martin, Laetitia J., Zoephel, Andreas, Mayer, Moriz, Gollner, Andreas, Covini, David, Fischer, Silke, Gerstberger, Thomas, Gmaschitz, Teresa, Goodwin, Craig, Greb, Peter, Häring, Daniela, Hela, Wolfgang, Hoffmann, Johann, Karolyi-Oezguer, Jale, Knesl, Petr, Kornigg, Stefan, Koegl, Manfred, Kousek, Roland, Lamarre, Lyne, Moser, Franziska, Munico-Martinez, Silvia, Peinsipp, Christoph, Phan, Jason, Rinnenthal, Jörg, Sai, Jiqing, Salamon, Christian, Scherbantin, Yvonne, Schipany, Katharina, Schnitzer, Renate, Schrenk, Andreas, Sharps, Bernadette, Siszler, Gabriella, Sun, Qi, Waterson, Alex, Wolkerstorfer, Bernhard, Zeeb, Markus, Pearson, Mark, Fesik, Stephen W., McConnell, Darryl B.
Foilsithe in Proc Natl Acad Sci U S A (2019)

Reply to Tran et al.: Dimeric KRAS protein–protein interaction stabilizers

le Kessler, Dirk, Gollner, Andreas, Gmachl, Michael, Mantoulidis, Andreas, Martin, Laetitia J., Zoephel, Andreas, Mayer, Moriz, Covini, David, Fischer, Silke, Gerstberger, Thomas, Gmaschitz, Teresa, Goodwin, Craig, Greb, Peter, Häring, Daniela, Hela, Wolfgang, Hoffmann, Johann, Karolyi-Oezguer, Jale, Knesl, Petr, Kornigg, Stefan, Koegl, Manfred, Kousek, Roland, Lamarre, Lyne, Moser, Franziska, Munico-Martinez, Silvia, Peinsipp, Christoph, Phan, Jason, Rinnenthal, Jörg, Sai, Jiqing, Salamon, Christian, Scherbantin, Yvonne, Schipany, Katharina, Schnitzer, Renate, Schrenk, Andreas, Sharps, Bernadette, Siszler, Gabriella, Sun, Qi, Waterson, Alex, Wolkerstorfer, Bernhard, Zeeb, Markus, Pearson, Mark, Fesik, Stephen W., McConnell, Darryl B.
Foilsithe in Proc Natl Acad Sci U S A (2020)