Total Syntheses of Arylindolizidine Alkaloids (+)-Ipalbidine and (+)-Antofine

by Niphakis, Micah J., Georg, Gunda I.
Published 2010

Synthesis of 6- and 7-membered cyclic enaminones: Scope and mechanism

by Niphakis, Micah J., Turunen, Brandon J., Georg, Gunda I.
Published 2010

Palladium(II)-Catalyzed Dehydrogenative Alkenylation of Cyclic Enaminones via the Fujiwara-Moritani Reaction

by Yu, Yi-Yun, Niphakis, Micah J., Georg, Gunda I.
Published 2011

A Copper-Assisted Palladium(II)-catalyzed Direct Arylation of Cyclic Enaminones with Arylboronic Acids

by Kim, Yong Wook, Niphakis, Micah J., Georg, Gunda I.
Published 2012

Determining target engagement in living systems

by Simon, Gabriel M., Niphakis, Micah J., Cravatt, Benjamin F.
Published 2013

Mapping the Protein Interaction Landscape for Fully Functionalized Small-Molecule Probes in Human Cells

by Kambe, Tohru, Correia, Bruno E., Niphakis, Micah J., Cravatt, Benjamin F.
Published 2014

O-Hydroxyacetamide Carbamates as a Highly Potent and Selective Class of Endocannabinoid Hydrolase Inhibitors

by Niphakis, Micah J., Johnson, Douglas S., Ballard, T. Eric, Stiff, Cory, Cravatt, Benjamin F.
Published 2011

Proteome-wide reactivity profiling identifies diverse carbamate chemotypes tuned for serine hydrolase inhibition

by Chang, Jae Won, Cognetta, Armand B., Niphakis, Micah J., Cravatt, Benjamin F.
Published 2013

Proteome-wide Mapping of Cholesterol-Interacting Proteins in Mammalian Cells

by Hulce, Jonathan J., Cognetta, Armand B., Niphakis, Micah J., Tully, Sarah E., Cravatt, Benjamin F.
Published 2013

Remodeling Natural Products: Chemistry and Serine Hydrolase Activity of a Rocaglate-Derived β-Lactone

by Lajkiewicz, Neil J., Cognetta, Armand B., Niphakis, Micah J., Cravatt, Benjamin F., Porco, John A.
Published 2014

Elevation of 2-AG by monoacylglycerol lipase inhibition in the visceral insular cortex interferes with anticipatory nausea in a rat model

by Limebeer, Cheryl L., Rock, Erin M., Puvanenthirarajah, Nirushan, Niphakis, Micah J., Cravatt, Benjamin F., Parker, Linda A.
Published in Behav Neurosci (2016)

Selective N-hydroxyhydantoin carbamate inhibitors of mammalian serine hydrolases

by Cognetta, Armand B., Niphakis, Micah J., Lee, Hyeon-Cheol, Martini, Michael L., Hulce, Jonathan J., Cravatt, Benjamin F.
Published in Chem Biol (2015)

Robust anti‐nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain

by Burston, James J, Mapp, Paul I, Sarmad, Sarir, Barrett, David A, Niphakis, Micah J, Cravatt, Benjamin F, Walsh, David A, Chapman, Victoria
Published in Br J Pharmacol (2016)

Double Dissociation of Monoacylglycerol Lipase Inhibition and CB(1) Antagonism in the Central Amygdala, Basolateral Amygdala, and the Interoceptive Insular Cortex on the Affective...

by Wills, Kiri L, Petrie, Gavin N, Millett, Geneva, Limebeer, Cheryl L, Rock, Erin M, Niphakis, Micah J, Cravatt, Benjamin F, Parker, Linda A
Published in Neuropsychopharmacology (2016)

The Endocannabinoid Hydrolysis Inhibitor SA-57: Intrinsic Antinociceptive Effects, Augmented Morphine-induced Antinociception, and Attenuated Heroin Seeking Behavior in Mice

by Wilkerson, Jenny L., Ghosh, Sudeshna, Mustafa, Mohammed, Abdullah, Rehab A., Niphakis, Micah J., Cabrera, Roberto, Maldonado, Rafael L., Cravatt, Benjamin F., Lichtman, Aron H.
Published in Neuropharmacology (2016)

Dual Inhibition of Endocannabinoid Catabolic Enzymes Produces Enhanced Antiwithdrawal Effects in Morphine-Dependent Mice

by Ramesh, Divya, Gamage, Thomas F, Vanuytsel, Tim, Owens, Robert A, Abdullah, Rehab A, Niphakis, Micah J, Shea-Donohue, Terez, Cravatt, Benjamin F, Lichtman, Aron H
Published 2013

Evaluation of NHS Carbamates as a Potent and Selective Class of Endocannabinoid Hydrolase Inhibitors

by Niphakis, Micah J., Cognetta, Armand B., Chang, Jae Won, Buczynski, Matthew W., Parsons, Loren H., Byrne, Frederika, Burston, James J., Chapman, Victoria, Cravatt, Benjamin F.
Published 2013

Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS

by Hermes, Douglas J., Xu, Changqing, Poklis, Justin L., Niphakis, Micah J., Cravatt, Benjamin F., Mackie, Ken, Lichtman, Aron H., Ignatowska-Jankowska, Bogna M., Fitting, Sylvia
Published in Neuropharmacology (2018)

Facile synthesis of borofragments and their evaluation in activity-based protein profiling

by Adachi, Shinya, Cognetta, Armand B., Niphakis, Micah J., He, Zhi, Zajdlik, Adam, St Denis, Jeffrey D., Scully, Conor C. G., Cravatt, Benjamin F., Yudin, Andrei K.
Published in Chem Commun (Camb) (2015)

Remarkably selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates

by Chang, Jae Won, Niphakis, Micah J., Lum, Kenneth M., Cognetta, Armand B., Wang, Chu, Matthews, Megan L., Niessen, Sherry, Buczynski, Matthew W., Parsons, Loren H., Cravatt, Benjamin F.
Published 2012