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Facile synthesis of borofragments and their evaluation in activity-based protein profiling
The discovery of enzyme inhibitors relies on synthetic methods that enable rapid and modular construction of small molecules. Heterocyclic fragments designed to maximize enthalpic interactions with their protein targets represent a particularly desirable class of molecules. Here we describe a reagen...
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Publicado no: | Chem Commun (Camb) |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4330092/ https://ncbi.nlm.nih.gov/pubmed/25633248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc09107h |
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