Bayes factor Bayesian mixed-effect model CpG sites DNA methylation GEE Ordinal responses RNA-seq bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general bic Book Industry Communication::P Mathematics & science boosting classification classification boundary clustering analysis convolutional neural networks deep learning expectation-maximization algorithm false discovery rate control feed-forward neural networks gaussian finite mixture model gene expression gene regulatory network gene set enrichment analysis integrative analysis kernel method lipid–environment interaction longitudinal lipidomics study machine learning multiple cancer types n/a network substructure