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Enantioselective α-functionalizations of ketones via allylic substitution of silyl enol ethers
The enantioselective construction of carbon–heteroatom and carbon–carbon bonds alpha to ketones forms substructures that are ubiquitous in natural products, pharmaceuticals and agrochemicals. Traditional methods to form such bonds have relied on combining ketone enolates with electrophiles. Reaction...
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| Publicado no: | Nat Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6347495/ https://ncbi.nlm.nih.gov/pubmed/30455430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-018-0165-x |
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