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Diastereo- and Enantioselective Iridium-Catalyzed Allylation of Cyclic Ketone Enolates: Synergetic Effect of Ligands and Barium Enolates

[Image: see text] We report asymmetric allylic alkylation of barium enolates of cyclic ketones catalyzed by a metallacyclic iridium complex containing a phosphoramidite ligand derived from (R)-1-(2-naphthyl)ethylamine. The reaction products contain adjacent quaternary and tertiary stereocenters. Thi...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Chen, Wenyong, Chen, Ming, Hartwig, John F.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235373/
https://ncbi.nlm.nih.gov/pubmed/25337972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja506500u
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