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Determining target engagement in living systems
Chemical probes are critical tools for elucidating the biological functions of proteins and can lead to new medicines for treating disease. The pharmacological validation of protein function requires verification that chemical probes engage their intended targets in vivo. Here we discuss technologie...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004587/ https://ncbi.nlm.nih.gov/pubmed/23508173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1211 |
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