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ABHD4 regulates multiple classes of N-acyl phospholipids in the mammalian central nervous system

N-acyl phospholipids are atypical components of cell membranes that bear three acyl chains and serve as potential biosynthetic precursors for lipid mediators such as endocannabinoids. Biochemical studies have implicated ABHD4 as a brain N-acyl phosphatidylethanolamine (NAPE) lipase, but in vivo evid...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Lee, Hyeon-Cheol, Simon, Gabriel M., Cravatt, Benjamin F.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767004/
https://ncbi.nlm.nih.gov/pubmed/25853435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00207
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