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Total Syntheses of Arylindolizidine Alkaloids (+)-Ipalbidine and (+)-Antofine

[Image: see text] This paper presents the first application of two recently developed reactions to natural product synthesis. The first method involves a 6-endo-trig cyclization to prepare a versatile chiral enaminone building block. The second is a direct C–H arylation reaction. As a showcase for t...

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Detalhes bibliográficos
Main Authors: Niphakis, Micah J., Georg, Gunda I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948484/
https://ncbi.nlm.nih.gov/pubmed/20704319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo101051w
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