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Total synthesis of (+)-antofine and (-)-cryptopleurine
The tylophorine alkaloid anticancer compounds antofine and cryptopleurine have been synthesized in optically active form. Both syntheses employ optically pure α-amino acids as the starting materials, require only seven steps from known 2-ethynylpyrrolidine or 2-ethynylpiperidine derivatives, and are...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3864684/ https://ncbi.nlm.nih.gov/pubmed/24357989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201300200 |
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