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The Endocannabinoid Hydrolysis Inhibitor SA-57: Intrinsic Antinociceptive Effects, Augmented Morphine-induced Antinociception, and Attenuated Heroin Seeking Behavior in Mice

Although opioids are highly efficacious analgesics, their abuse potential and other untoward side effects diminish their therapeutic utility. The addition of non-opioid analgesics offers a promising strategy to reduce required antinociceptive opioid doses that concomitantly reduce opioid-related sid...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Wilkerson, Jenny L., Ghosh, Sudeshna, Mustafa, Mohammed, Abdullah, Rehab A., Niphakis, Micah J., Cabrera, Roberto, Maldonado, Rafael L., Cravatt, Benjamin F., Lichtman, Aron H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289715/
https://ncbi.nlm.nih.gov/pubmed/27890602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.11.015
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