The Endocannabinoid Hydrolysis Inhibitor SA-57: Intrinsic Antinociceptive Effects, Augmented Morphine-induced Antinociception, and Attenuated Heroin Seeking Behavior in Mice

Although opioids are highly efficacious analgesics, their abuse potential and other untoward side effects diminish their therapeutic utility. The addition of non-opioid analgesics offers a promising strategy to reduce required antinociceptive opioid doses that concomitantly reduce opioid-related sid...

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Publicat a:Neuropharmacology
Autors principals: Wilkerson, Jenny L., Ghosh, Sudeshna, Mustafa, Mohammed, Abdullah, Rehab A., Niphakis, Micah J., Cabrera, Roberto, Maldonado, Rafael L., Cravatt, Benjamin F., Lichtman, Aron H.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289715/
https://ncbi.nlm.nih.gov/pubmed/27890602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.11.015
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