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Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice

BACKGROUND: Inhibition of endocannabinoid catabolic enzymes fatty acid amide hydrolase (FAAH) and/or monoacylglycerol lipase (MAGL) reduces somatic morphine withdrawal signs, but its effects on aversive aspects of withdrawal are unknown. The present study investigated whether Δ(9)-tetrahydrocannabin...

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Detalhes bibliográficos
Publicado no:Drug Alcohol Depend
Main Authors: Gamage, Thomas F., Ignatowska-Jankowska, Bogna M., Muldoon, Pretal P., Cravatt, Benjamin F., Damaj, M. Imad, Lichtman, Aron H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295928/
https://ncbi.nlm.nih.gov/pubmed/25479915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2014.11.015
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