Fragment Screening by Surface Plasmon Resonance

por Navratilova, Iva, Hopkins, Andrew L.
Publicado em 2010

Black Swans and white tablets

por Oprea, Tudor I, Hopkins, Andrew L
Publicado no Chem Cent J (2008)

Screening for GPCR Ligands Using Surface Plasmon Resonance

por Navratilova, Iva, Besnard, Jérémy, Hopkins, Andrew L.
Publicado em 2011

Quantifying the chemical beauty of drugs

por Bickerton, G. Richard, Paolini, Gaia V., Besnard, Jérémy, Muresan, Sorel, Hopkins, Andrew L.
Publicado em 2012

Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening

por Navratilova, Iva, Aristotelous, Tonia, Picaud, Sarah, Chaikuad, Apirat, Knapp, Stefan, Filappakopoulos, Panagis, Hopkins, Andrew L.
Publicado no ACS Med Chem Lett (2016)

Rapid Analysis of Pharmacology for Infectious Diseases

por Hopkins, Andrew L, Bickerton, G. Richard, Carruthers, Ian M, Boyer, Stephen K, Rubin, Harvey, Overington, John P
Publicado em 2011

Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleo...

por Esnouf, Robert M., Ren, Jingshan, Hopkins, Andrew L., Ross, Carl K., Jones, E. Yvonne, Stammers, David K., Stuart, David I.
Publicado em 1997

Application of RNAi to Genomic Drug Target Validation in Schistosomes

por Guidi, Alessandra, Mansour, Nuha R., Paveley, Ross A., Carruthers, Ian M., Besnard, Jérémy, Hopkins, Andrew L., Gilbert, Ian H., Bickle, Quentin D.
Publicado no PLoS Negl Trop Dis (2015)

Validity of Ligand Efficiency Metrics

por Murray, Christopher W., Erlanson, Daniel A., Hopkins, Andrew L., Keserü, György M., Leeson, Paul D., Rees, David C., Reynolds, Charles H., Richmond, Nicola J.
Publicado em 2014

Whole Organism High-Content Screening by Label-Free, Image-Based Bayesian Classification for Parasitic Diseases

por Paveley, Ross A., Mansour, Nuha R., Hallyburton, Irene, Bleicher, Leo S., Benn, Alex E., Mikic, Ivana, Guidi, Alessandra, Gilbert, Ian H., Hopkins, Andrew L., Bickle, Quentin D.
Publicado em 2012

3′-Azido-3′-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes

por Ren, Jingshan, Esnouf, Robert M., Hopkins, Andrew L., Jones, E. Yvonne, Kirby, Ian, Keeling, James, Ross, Carl K., Larder, Brendan A., Stuart, David I., Stammers, David K.
Publicado em 1998

A Crowdsourcing Evaluation of the NIH Chemical Probes

por Oprea, Tudor I., Bologa, Cristian G., Boyer, Scott, Curpan, Ramona F., Glen, Robert C., Hopkins, Andrew L., Lipinski, Christopher A., Marshall, Garland R., Martin, Yvonne C., Ostopovici-Halip, Liliana, Rishton, Gilbert, Ursu, Oleg, Vaz, Roy J., Waller, Chris, Waldmann, Herbert, Sklar, Larry A.
Publicado em 2009

Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor

por Aristotelous, Tonia, Ahn, Seungkirl, Shukla, Arun K., Gawron, Sylwia, Sassano, Maria F., Kahsai, Alem W., Wingler, Laura M., Zhu, Xiao, Tripathi-Shukla, Prachi, Huang, Xi-Ping, Riley, Jennifer, Besnard, Jérémy, Read, Kevin D., Roth, Bryan L., Gilbert, Ian H., Hopkins, Andrew L., Lefkowitz, Robert J., Navratilova, Iva
Publicado em 2013

Automated design of ligands to polypharmacological profiles

por Besnard, Jérémy, Ruda, Gian Filippo, Setola, Vincent, Abecassis, Keren, Rodriguiz, Ramona M., Huang, Xi-Ping, Norval, Suzanne, Sassano, Maria F., Shin, Antony I., Webster, Lauren A., Simeons, Frederick R.C., Stojanovski, Laste, Prat, Annik, Seidah, Nabil G., Constam, Daniel B., Bickerton, G. Richard, Read, Kevin D., Wetsel, William C., Gilbert, Ian H., Roth, Bryan L., Hopkins, Andrew L.
Publicado em 2012

Genomic-scale prioritization of drug targets: the TDR Targets database

por Agüero, Fernán, Al-Lazikani, Bissan, Aslett, Martin, Berriman, Matthew, Buckner, Frederick S., Campbell, Robert K., Carmona, Santiago, Carruthers, Ian M., Chan, A. W. Edith, Chen, Feng, Crowther, Gregory J., Doyle, Maria A., Hertz-Fowler, Christiane, Hopkins, Andrew L., McAllister, Gregg, Nwaka, Solomon, Overington, John P., Pain, Arnab, Paolini, Gaia V., Pieper, Ursula, Ralph, Stuart A., Riechers, Aaron, Roos, David S., Sali, Andrej, Shanmugam, Dhanasekaran, Suzuki, Takashi, Voorhis, Wesley C. Van, Verlinde, Christophe L. M. J.
Publicado em 2008

Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19

por Redhead, Martin A., Owen, C. David, Brewitz, Lennart, Collette, Amelia H., Lukacik, Petra, Strain-Damerell, Claire, Robinson, Sean W., Collins, Patrick M., Schäfer, Philipp, Swindells, Mark, Radoux, Chris J., Hopkins, Iva Navratilova, Fearon, Daren, Douangamath, Alice, von Delft, Frank, Malla, Tika R., Vangeel, Laura, Vercruysse, Thomas, Thibaut, Jan, Leyssen, Pieter, Nguyen, Tu-Trinh, Hull, Mitchell, Tumber, Anthony, Hallett, David J., Schofield, Christopher J., Stuart, David I., Hopkins, Andrew L., Walsh, Martin A.
Publicado no Sci Rep (2021)