The relationship between target-class and the physicochemical properties of antibacterial drugs

по Mugumbate, Grace, Overington, John P.
Опубликовано в: Bioorg Med Chem (2015)

Classification and analysis of a large collection of in vivo bioassay descriptions

по Zwierzyna, Magdalena, Overington, John P.
Опубликовано в: PLoS Comput Biol (2017)

Global Analysis of Small Molecule Binding to Related Protein Targets

по Kruger, Felix A., Overington, John P.
Опубликовано 2012

Computational and Practical Aspects of Drug Repositioning

по Oprea, Tudor I., Overington, John P.
Опубликовано в: Assay Drug Dev Technol (2015)

Mapping small molecule binding data to structural domains

по Kruger, Felix A, Rostom, Raghd, Overington, John P
Опубликовано 2012

Brain: biomedical knowledge manipulation

по Croset, Samuel, Overington, John P., Rebholz-Schuhmann, Dietrich
Опубликовано 2013

The functional therapeutic chemical classification system

по Croset, Samuel, Overington, John P., Rebholz-Schuhmann, Dietrich
Опубликовано 2014

Activity, assay and target data curation and quality in the ChEMBL database

по Papadatos, George, Gaulton, Anna, Hersey, Anne, Overington, John P.
Опубликовано в: J Comput Aided Mol Des (2015)

Chemical, Target, and Bioactive Properties of Allosteric Modulation

по van Westen, Gerard J. P., Gaulton, Anna, Overington, John P.
Опубликовано 2014

Towards predictive resistance models for agrochemicals by combining chemical and protein similarity via proteochemometric modelling

по van Westen, Gerard J. P., Bender, Andreas, Overington, John P.
Опубликовано 2014

PPDMs—a resource for mapping small molecule bioactivities from ChEMBL to Pfam-A protein domains

по Kruger, Felix A., Gaulton, Anna, Nowotka, Michal, Overington, John P.
Опубликовано в: Bioinformatics (2015)

myChEMBL: a virtual machine implementation of open data and cheminformatics tools

по Ochoa, Rodrigo, Davies, Mark, Papadatos, George, Atkinson, Francis, Overington, John P.
Опубликовано 2014

UniChem: extension of InChI-based compound mapping to salt, connectivity and stereochemistry layers

по Chambers, Jon, Davies, Mark, Gaulton, Anna, Papadatos, George, Hersey, Anne, Overington, John P
Опубликовано 2014

Rational design of non-resistant targeted cancer therapies

по Martínez-Jiménez, Francisco, Overington, John P., Al-Lazikani, Bissan, Marti-Renom, Marc A.
Опубликовано в: Sci Rep (2017)

Chemical Databases: Curation or Integration by User-Defined Equivalence?

по Hersey, Anne, Chambers, Jon, Bellis, Louisa, Patricia Bento, A., Gaulton, Anna, Overington, John P
Опубликовано в: Drug Discov Today Technol (2015)

A document classifier for medicinal chemistry publications trained on the ChEMBL corpus

по Papadatos, George, van Westen, Gerard JP, Croset, Samuel, Santos, Rita, Trubian, Simone, Overington, John P
Опубликовано 2014

A drug target slim: using gene ontology and gene ontology annotations to navigate protein-ligand target space in ChEMBL

по Mutowo, Prudence, Bento, A. Patrícia, Dedman, Nathan, Gaulton, Anna, Hersey, Anne, Lomax, Jane, Overington, John P.
Опубликовано в: J Biomed Semantics (2016)

PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease

по Schmidt, Amand F, Pearce, Lucy S, Wilkins, John T, Overington, John P, Hingorani, Aroon D, Casas, Juan P
Опубликовано в: Cochrane Database Syst Rev (2017)

Rapid Analysis of Pharmacology for Infectious Diseases

по Hopkins, Andrew L, Bickerton, G. Richard, Carruthers, Ian M, Boyer, Stephen K, Rubin, Harvey, Overington, John P
Опубликовано 2011

ChEMBL web services: streamlining access to drug discovery data and utilities

по Davies, Mark, Nowotka, Michał, Papadatos, George, Dedman, Nathan, Gaulton, Anna, Atkinson, Francis, Bellis, Louisa, Overington, John P.
Опубликовано в: Nucleic Acids Res (2015)