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A drug target slim: using gene ontology and gene ontology annotations to navigate protein-ligand target space in ChEMBL

BACKGROUND: The process of discovering new drugs is a lengthy, time-consuming and expensive process. Modern day drug discovery relies heavily on the rapid identification of novel ‘targets’, usually proteins that can be modulated by small molecule drugs to cure or minimise the effects of a disease. O...

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Detalhes bibliográficos
Publicado no:J Biomed Semantics
Main Authors: Mutowo, Prudence, Bento, A. Patrícia, Dedman, Nathan, Gaulton, Anna, Hersey, Anne, Lomax, Jane, Overington, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039825/
https://ncbi.nlm.nih.gov/pubmed/27678076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13326-016-0102-0
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