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Fragment Screening by Surface Plasmon Resonance
[Image: see text] Fragment-based drug discovery is a validated approach for the discovery of drug candidates. However, the weak affinity of fragment compounds requires highly sensitive biophysical techniques, such as nuclear magnetic resonance (NMR) or X-ray crystallography, to identify hits. Thus t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007845/ https://ncbi.nlm.nih.gov/pubmed/24900174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml900002k |
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