Is Nuclear Factor Erythroid 2–Related Factor 2 Responsible for Sex Differences in Susceptibility to Acetaminophen-Induced Hepatotoxicity in Mice?

Por Rohrer, Philip R., Rudraiah, Swetha, Goedken, Michael J., Manautou, José E.
Publicado em 2014

Acquired Resistance to Acetaminophen Hepatotoxicity is Associated with Induction of Multidrug Resistance-Associated Protein 4 (Mrp4) in Proliferating Hepatocytes

Por Aleksunes, Lauren M., Campion, Sarah N., Goedken, Michael J., Manautou, José E.
Publicado em 2008

Multidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of Diclofenac

Por Scialis, Renato J., Csanaky, Iván L., Goedken, Michael J., Manautou, José E.
Publicado no Drug Metab Dispos (2015)

Lack of multidrug resistance-associated protein 4 (Mrp4) alters the kinetics of acetaminophen toxicity

Por Donepudi, Ajay C, Goedken, Michael J., Schuetz, John D., E Manautou, José
Publicado no Toxicol Rep (2019)

Compensatory Induction of Liver Efflux Transporters in Response to ANIT-Induced Liver Injury Is Impaired in FXR-Null Mice

Por Cui, Yue J., Aleksunes, Lauren M., Tanaka, Yuji, Goedken, Michael J., Klaassen, Curtis D.
Publicado em 2009

Nuclear Factor Erythroid 2-Related Factor 2 Deletion Impairs Glucose Tolerance and Exacerbates Hyperglycemia in Type 1 Diabetic Mice

Por Aleksunes, Lauren M., Reisman, Scott A., Yeager, Ronnie L., Goedken, Michael J., Klaassen, Curtis D.
Publicado em 2010

Pregnancy Represses Induction of Efflux Transporters in Livers of Type I Diabetic Mice

Por Aleksunes, Lauren M., Xu, Jialin, Lin, Eugenia, Wen, Xia, Goedken, Michael J., Slitt, Angela L.
Publicado em 2013

In vivo cytochrome P450 activity alterations in diabetic nonalcoholic steatohepatitis mice

Por Li, Hui, Clarke, John D., Dzierlenga, Anika L., Bear, John, Goedken, Michael J., Cherrington, Nathan J.
Publicado no J Biochem Mol Toxicol (2016)

Transcriptional Regulation of Renal Cytoprotective Genes by Nrf2 and Its Potential Use as a Therapeutic Target to Mitigate Cisplatin-Induced Nephrotoxicity

Por Aleksunes, Lauren M., Goedken, Michael J., Rockwell, Cheryl E., Thomale, Juergen, Manautou, Jose E., Klaassen, Curtis D.
Publicado em 2010

Systems Level Metabolic Phenotype of Methotrexate Administration in the Context of Non-alcoholic Steatohepatitis in the Rat

Por Kyriakides, Michael, Hardwick, Rhiannon N., Jin, Zhaosheng, Goedken, Michael J., Holmes, Elaine, Cherrington, Nathan J., Coen, Muireann
Publicado no Toxicol Sci (2014)

Enhanced Hepatotoxicity by Acetaminophen in Vanin-1 Knockout Mice is Associated with Deficient Proliferative and Immune Responses

Por Ferreira, Daniel W., Goedken, Michael J., Rommelaere, Samuel, Chasson, Lionel, Galland, Franck, Naquet, Philippe, Manautou, José E.
Publicado no Biochim Biophys Acta (2016)

Acute feeding suppression and toxicity of raspberry ketone [4-(4-hydroxyphenyl)-2-butanone] in mice.

Por Hao, Lihong, Kshatriya, Dushyant, Li, Xinyi, Badrinath, Aditi, Szmacinski, Zuzanna, Goedken, Michael J., Polunas, Marianne, Bello, Nicholas T.
Publicado no Food Chem Toxicol (2020)

MDR1 Transporter Protects Against Paraquat-Induced Toxicity in Human and Mouse Proximal Tubule Cells

Por Wen, Xia, Gibson, Christopher J., Yang, Ill, Buckley, Brian, Goedken, Michael J., Richardson, Jason R., Aleksunes, Lauren M.
Publicado no Toxicol Sci (2014)

Tolerance to Acetaminophen Hepatotoxicity in the Mouse Model of Autoprotection Is Associated with Induction of Flavin-Containing Monooxygenase-3 (FMO3) in Hepatocytes

Por Rudraiah, Swetha, Rohrer, Philip R., Gurevich, Igor, Goedken, Michael J., Rasmussen, Theodore, Hines, Ronald N., Manautou, José E.
Publicado no Toxicol Sci (2014)

Coordinated Induction of Nrf2 Target Genes Protects Against Iron Nitrilotriacetate (FeNTA)-Induced Nephrotoxicity

Por Tanaka, Yuji, Aleksunes, Lauren M., Goedken, Michael J., Chen, Chuan, Reisman, Scott A., Manautou, José E., Klaassen, Curtis D.
Publicado em 2008

Mechanism of Altered Metformin Distribution in Nonalcoholic Steatohepatitis

Por Clarke, John D., Dzierlenga, Anika L., Nelson, Nicholas R., Li, Hui, Werts, Samantha, Goedken, Michael J., Cherrington, Nathan J.
Publicado no Diabetes (2015)

Transgenic Expression of the Human MRP2 Transporter Reduces Cisplatin Accumulation and Nephrotoxicity in Mrp2-Null Mice

Por Wen, Xia, Buckley, Brian, McCandlish, Elizabeth, Goedken, Michael J., Syed, Samira, Pelis, Ryan, Manautou, José E., Aleksunes, Lauren M.
Publicado em 2014

Synergistic interaction between genetics and disease on pravastatin disposition

Por Clarke, John D., Hardwick, Rhiannon N., Lake, April D., Lickteig, Andrew J., Goedken, Michael J., Klaassen, Curtis D., Cherrington, Nathan J.
Publicado em 2014

Renal Xenobiotic Transporter Expression is Altered in Multiple Experimental Models of Nonalcoholic Steatohepatitis

Por Canet, Mark J., Hardwick, Rhiannon N., Lake, April D., Dzierlenga, Anika L., Clarke, John D., Goedken, Michael J., Cherrington, Nathan J.
Publicado no Drug Metab Dispos (2015)

Effect of allyl alcohol on hepatic transporter expression: Zonal patterns of expression and role of Kupffer cell function

Por Campion, Sarah N., Tatis-Rios, Cristina, Augustine, Lisa M., Goedken, Michael J., van Rooijen, Nico, Cherrington, Nathan J., Manautou, José E.
Publicado no Toxicol Appl Pharmacol (2009)