ABC Transporters and their Role in Nucleoside and Nucleotide Drug Resistance

Por Fukuda, Yu, Schuetz, John D.
Publicado em 2012

Tobacco Carcinogen NNK Transporter MRP2 Regulates CFTR Function in Lung Epithelia: Implications for Lung Cancer

Por Li, Chunying, Schuetz, John D., Naren, Anjaparavanda P.
Publicado em 2010

Environmental Xenobiotics and the Antihormones Cyproterone Acetate and Spironolactone Use the Nuclear Hormone Pregnenolone X Receptor to Activate the CYP3A23 Hormone Response Eleme...

Por SCHUETZ, ERIN G., BRIMER, CYNTHIA, SCHUETZ, JOHN D.
Publicado em 1998

The Role of Transporters in Toxicity and Disease

Por Schuetz, John D., Swaan, Peter W., Tweedie, Donald J.
Publicado em 2014

Cell survival under stress is enhanced by a mitochondrial ATP-binding cassette transporter that regulates hemoproteins

Por Lynch, John, Fukuda, Yu, Krishnamurthy, Partha, Du, Guoqing, Schuetz, John D.
Publicado em 2009

p53-dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents

Por Thottassery, Jaideep V., Zambetti, Gerard P., Arimori, Kazuhiko, Schuetz, Erin G., Schuetz, John D.
Publicado em 1997

Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo

Por Zhou, Sheng, Morris, John J., Barnes, Yuxiao, Lan, Lubin, Schuetz, John D., Sorrentino, Brian P.
Publicado em 2002

Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

Por Zelcer, Noam, Reid, Glen, Wielinga, Peter, Kuil, Annemieke, van der Heijden, Ingrid, Schuetz, John D, Borst, Piet
Publicado em 2003

Forskolin Modifies Retinal Vascular Development in Mrp4-Knockout Mice

Por Matsumiya, Wataru, Kusuhara, Sentaro, Hayashibe, Keiko, Maruyama, Kazuichi, Kusuhara, Hiroyuki, Tagami, Mizuki, Schuetz, John D., Negi, Akira
Publicado em 2012

Deoxycytidine kinase modulates the impact of the ABC transporter ABCG2 on clofarabine cytotoxicity

Por Nagai, Shinjiro, Takenaka, Kazumasa, Nachagari, Deepa, Rose, Charles, Domoney, Kali, Sun, Daxi, Sparreboom, Alex, Schuetz, John D.
Publicado em 2011

Cyclic Nucleotide Compartmentalization: Contributions of Phosphodiesterases and ATP-Binding Cassette Transporters

Por Cheepala, Satish, Hulot, Jean-Sebastien, Morgan, Jessica A., Sassi, Yassine, Zhang, Weiqiang, Naren, Anjaparavanda P., Schuetz, John D.
Publicado no Annu Rev Pharmacol Toxicol (2012)

Conserved Intramolecular Disulfide Bond Is Critical to Trafficking and Fate of ATP-binding Cassette (ABC) Transporters ABCB6 and Sulfonylurea Receptor 1 (SUR1)/ABCC8

Por Fukuda, Yu, Aguilar-Bryan, Lydia, Vaxillaire, Martine, Dechaume, Aurelie, Wang, Yao, Dean, Michael, Moitra, Karobi, Bryan, Joseph, Schuetz, John D.
Publicado em 2011

The Absence of Mrp4 Has No Effect on the Recruitment of Neutrophils and Eosinophils into the Lung after LPS, Cigarette Smoke or Allergen Challenge

Por Schymeinsky, Jürgen, Mayer, Hannah, Tomsic, Christopher, Tilp, Cornelia, Schuetz, John D., Cui, Yunhai, Wollin, Lutz, Gantner, Florian, Erb, Klaus J.
Publicado em 2013

Deletion of MCL-1 causes lethal cardiac failure and mitochondrial dysfunction

Por Wang, Xi, Bathina, Madhavi, Lynch, John, Koss, Brian, Calabrese, Christopher, Frase, Sharon, Schuetz, John D., Rehg, Jerold E., Opferman, Joseph T.
Publicado em 2013

Human Immunodeficiency Virus Protease Inhibitors Interact with ATP Binding Cassette Transporter 4/Multidrug Resistance Protein 4: A Basis for Unanticipated Enhanced Cytotoxicity

Por Fukuda, Yu, Takenaka, Kazumasa, Sparreboom, Alex, Cheepala, Satish B., Wu, Chung-Pu, Ekins, Sean, Ambudkar, Suresh V., Schuetz, John D.
Publicado em 2013

Crucial Role for Phylogenetically Conserved Cytoplasmic Loop 3 in ABCC4 Protein Expression

Por Cheepala, Satish B., Bao, Ju, Nachagari, Deepa, Sun, Daxi, Wang, Yao, Zhong, Tao, Naren, Anjaparavanda P., Zheng, Jie, Schuetz, John D.
Publicado em 2013

Multi-drug Resistance Protein 4 (MRP4)-mediated Regulation of Fibroblast Cell Migration Reflects a Dichotomous Role of Intracellular Cyclic Nucleotides

Por Sinha, Chandrima, Ren, Aixia, Arora, Kavisha, Moon, Chang-Suk, Yarlagadda, Sunitha, Zhang, Weiqiang, Cheepala, Satish B., Schuetz, John D., Naren, Anjaparavanda P.
Publicado em 2013

Crucial role for phylogenetically conserved cytoplasmic loop 3 in ABCC4 protein expression.

Por Cheepala, Satish B., Bao, Ju, Nachagari, Deepa, Sun, Daxi, Wang, Yao, Zhong, Tao P., Naren, Anjaparavanda P., Zheng, Jie, Schuetz, John D.
Publicado em 2013

PKA and Actin Play Critical Roles as Downstream Effectors in MRP4-Mediated Regulation of Fibroblast Migration

Por Sinha, Chandrima, Ren, Aixia, Arora, Kavisha, Moon, Chang Suk, Yarlagadda, Sunitha, Woodrooffe, Koryse, Lin, Songbai, Schuetz, John D., Ziady, Assem G., Naren, Anjaparavanda P.
Publicado no Cell Signal (2015)

The ABCC4 membrane transporter modulates platelet aggregation

Por Cheepala, Satish B., Pitre, Aaron, Fukuda, Yu, Takenaka, Kazumasa, Zhang, Yuanyuan, Wang, Yao, Frase, Sharon, Pestina, Tamara, Gartner, T. Kent, Jackson, Carl, Schuetz, John D.
Publicado no Blood (2015)