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Cell survival under stress is enhanced by a mitochondrial ATP-binding cassette transporter that regulates hemoproteins
The ATP binding cassette (ABC) transporter ABCB6 localizes to the mitochondria, where it imports porphyrins and upregulates de novo porphyrin synthesis. If ABCB6 also increases the intracellular heme concentration, it may broadly affect the regulation and physiology of cellular hemoproteins. We test...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326408/ https://ncbi.nlm.nih.gov/pubmed/19549895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0078 |
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