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Tobacco Carcinogen NNK Transporter MRP2 Regulates CFTR Function in Lung Epithelia: Implications for Lung Cancer

Lung cancer is the leading cause of cancer death in the United States. About 85% of all lung cancers are linked to tobacco smoke, in which more than 50 lung carcinogens have been identified and one of the most abundant is 4-(methylnitrosamino)-1-(3-pyridyl)- 1-butanone (NNK). The human lung epitheli...

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Detalhes bibliográficos
Main Authors: Li, Chunying, Schuetz, John D., Naren, Anjaparavanda P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868381/
https://ncbi.nlm.nih.gov/pubmed/20089353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2009.12.009
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