Conserved Intramolecular Disulfide Bond Is Critical to Trafficking and Fate of ATP-binding Cassette (ABC) Transporters ABCB6 and Sulfonylurea Receptor 1 (SUR1)/ABCC8

The ATP-binding cassette (ABC) transporter ABCB6 is a mitochondrial porphyrin transporter that activates porphyrin biosynthesis. ABCB6 lacks a canonical mitochondrial targeting sequence but reportedly traffics to other cellular compartments such as the plasma membrane. How ABCB6 reaches these destin...

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Detalhes bibliográficos
Main Authors: Fukuda, Yu, Aguilar-Bryan, Lydia, Vaxillaire, Martine, Dechaume, Aurelie, Wang, Yao, Dean, Michael, Moitra, Karobi, Bryan, Joseph, Schuetz, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048732/
https://ncbi.nlm.nih.gov/pubmed/21199866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.174516
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