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Variation and evolution of the ABC transporter genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: implication for pharmacogenetics and disease

The ATP-binding cassette (ABC) transporter genes are ubiquitous in the genomes of all vertebrates. Some of these transporters play a key role in xenobiotic defense and are endowed with the capacity to effl ux harmful toxic substances. A major role in the evolution of the vertebrate ABC genes is play...

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Détails bibliographiques
Publié dans:Drug Metabol Drug Interact
Auteurs principaux: Silverton, Latoya, Dean, Michael, Moitra, Karobi
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372709/
https://ncbi.nlm.nih.gov/pubmed/22098604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/DMDI.2011.027
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