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Variation and evolution of the ABC transporter genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: implication for pharmacogenetics and disease
The ATP-binding cassette (ABC) transporter genes are ubiquitous in the genomes of all vertebrates. Some of these transporters play a key role in xenobiotic defense and are endowed with the capacity to effl ux harmful toxic substances. A major role in the evolution of the vertebrate ABC genes is play...
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| Veröffentlicht in: | Drug Metabol Drug Interact |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7372709/ https://ncbi.nlm.nih.gov/pubmed/22098604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/DMDI.2011.027 |
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