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Variation and evolution of the ABC transporter genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: implication for pharmacogenetics and disease

The ATP-binding cassette (ABC) transporter genes are ubiquitous in the genomes of all vertebrates. Some of these transporters play a key role in xenobiotic defense and are endowed with the capacity to effl ux harmful toxic substances. A major role in the evolution of the vertebrate ABC genes is play...

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Bibliografiska uppgifter
I publikationen:Drug Metabol Drug Interact
Huvudupphovsmän: Silverton, Latoya, Dean, Michael, Moitra, Karobi
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372709/
https://ncbi.nlm.nih.gov/pubmed/22098604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/DMDI.2011.027
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