Загрузка...
Investigation of the importance of multidrug resistance-associated protein 4 (Mrp4/Abcc4) in the active efflux of anionic drugs across the blood–brain barrier
The importance of multidrug resistance-associated protein 4 (Mrp4/Abcc4) in limiting the penetration of Mrp4 substrate compounds into the central nervous system across the blood–brain barrier (BBB) was investigated using Mrp4(-/-) mice. Significant ATP-dependent uptake by MRP4 was observed for ochra...
Сохранить в:
| Опубликовано в: : | J Pharm Sci |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5955602/ https://ncbi.nlm.nih.gov/pubmed/28456721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.04.040 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|