Impaired N-linked Glycosylation of Uptake and Efflux Transporters in Human Nonalcoholic Fatty Liver Disease

Por Clarke, John D, Novak, Petr, Lake, April D, Hardwick, Rhiannon N, Cherrington, Nathan J
Publicado no Liver Int (2017)

Diversity in Antioxidant Response Enzymes in Progressive Stages of Human Nonalcoholic Fatty Liver Disease

Por Hardwick, Rhiannon N., Fisher, Craig D., Canet, Mark J., Lake, April D., Cherrington, Nathan J.
Publicado em 2010

Variations in ATP-Binding Cassette Transporter Regulation during the Progression of Human Nonalcoholic Fatty Liver Disease

Por Hardwick, Rhiannon N., Fisher, Craig D., Canet, Mark J., Scheffer, George L., Cherrington, Nathan J.
Publicado em 2011

Molecular Mechanism of Altered Ezetimibe Disposition in Nonalcoholic Steatohepatitis

Por Hardwick, Rhiannon N., Fisher, Craig D., Street, Stephanie M., Canet, Mark J., Cherrington, Nathan J.
Publicado em 2012

Hepatic Basolateral Efflux Contributes Significantly to Rosuvastatin Disposition II: Characterization of Hepatic Elimination by Basolateral, Biliary, and Metabolic Clearance Pathwa...

Por Pfeifer, Nathan D., Bridges, Arlene S., Ferslew, Brian C., Hardwick, Rhiannon N., Brouwer, Kim L. R.
Publicado em 2013

Experimental Nonalcoholic Steatohepatitis Increases Exposure to Simvastatin Hydroxy Acid by Decreasing Hepatic Organic Anion Transporting Polypeptide Expression

Por Clarke, John D., Hardwick, Rhiannon N., Lake, April D., Canet, Mark J., Cherrington, Nathan J.
Publicado em 2014

Genetic variation in the mouse model of Niemann Pick C1 affects female, as well as male, adiposity, and hepatic bile transporters but has indeterminate effects on caveolae

Por Jelinek, David A, Maghsoodi, Bita, Borbon, Ivan A, Hardwick, Rhiannon N., Cherrington, Nathan J., Erickson, Robert P
Publicado em 2011

An Experimental Approach To Evaluate the Impact of Impaired Transport Function on Hepatobiliary Drug Disposition Using Mrp2-Deficient TR(–) Rat Sandwich-Cultured Hepatocytes in Com...

Por Yang, Kyunghee, Pfeifer, Nathan D., Hardwick, Rhiannon N., Yue, Wei, Stewart, Paul W., Brouwer, Kim L. R.
Publicado em 2014

Systems Level Metabolic Phenotype of Methotrexate Administration in the Context of Non-alcoholic Steatohepatitis in the Rat

Por Kyriakides, Michael, Hardwick, Rhiannon N., Jin, Zhaosheng, Goedken, Michael J., Holmes, Elaine, Cherrington, Nathan J., Coen, Muireann
Publicado no Toxicol Sci (2014)

Arsenite Activates NFκB Through Induction of C-Reactive Protein

Por Druwe, Ingrid L., Sollome, James J., Sanchez-Soria, Pablo, Hardwick, Rhiannon N., Camenisch, Todd D., Vaillancourt, Richard R.
Publicado em 2012

Basolateral Uptake of Nucleosides by Sertoli Cells Is Mediated Primarily by Equilibrative Nucleoside Transporter 1

Por Klein, David M., Evans, Kristen K., Hardwick, Rhiannon N., Dantzler, William H., Wright, Stephen H., Cherrington, Nathan J.
Publicado em 2013

The Adaptive Endoplasmic Reticulum Stress Response to Lipotoxicity in Progressive Human Nonalcoholic Fatty Liver Disease

Por Lake, April D., Novak, Petr, Hardwick, Rhiannon N., Flores-Keown, Brieanna, Zhao, Fei, Klimecki, Walter T., Cherrington, Nathan J.
Publicado em 2014

Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models

Por Canet, Mark J., Hardwick, Rhiannon N., Lake, April D., Dzierlenga, Anika L., Clarke, John D., Cherrington, Nathan J.
Publicado em 2014

Synergistic interaction between genetics and disease on pravastatin disposition

Por Clarke, John D., Hardwick, Rhiannon N., Lake, April D., Lickteig, Andrew J., Goedken, Michael J., Klaassen, Curtis D., Cherrington, Nathan J.
Publicado em 2014

Renal Xenobiotic Transporter Expression is Altered in Multiple Experimental Models of Nonalcoholic Steatohepatitis

Por Canet, Mark J., Hardwick, Rhiannon N., Lake, April D., Dzierlenga, Anika L., Clarke, John D., Goedken, Michael J., Cherrington, Nathan J.
Publicado no Drug Metab Dispos (2015)

Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease

Por Lake, April D., Novak, Petr, Fisher, Craig D., Jackson, Jonathan P., Hardwick, Rhiannon N., Billheimer, D. Dean, Klimecki, Walter T., Cherrington, Nathan J.
Publicado em 2011

The hepatic bile acid transporters Ntcp and Mrp2 are downregulated in experimental necrotizing enterocolitis

Por Cherrington, Nathan J., Estrada, Teresa E., Frisk, Harrison A., Canet, Mark J., Hardwick, Rhiannon N., Dvorak, Bohuslav, Lux, Katie, Halpern, Melissa D.
Publicado em 2013

Altered Arsenic Disposition in Experimental Nonalcoholic Fatty Liver Disease

Por Canet, Mark J., Hardwick, Rhiannon N., Lake, April D., Kopplin, Michael J., Scheffer, George L., Klimecki, Walter T., Gandolfi, A. Jay, Cherrington, Nathan J.
Publicado em 2012

Altered UDP-Glucuronosyltransferase and Sulfotransferase Expression and Function during Progressive Stages of Human Nonalcoholic Fatty Liver Disease

Por Hardwick, Rhiannon N., Ferreira, Daniel W., More, Vijay R., Lake, April D., Lu, Zhenqiang, Manautou, Jose E., Slitt, Angela L., Cherrington, Nathan J.
Publicado em 2013

Increased Susceptibility to Methotrexate-Induced Toxicity in Nonalcoholic Steatohepatitis

Por Hardwick, Rhiannon N., Clarke, John D., Lake, April D., Canet, Mark J., Anumol, Tarun, Street, Stephanie M., Merrell, Matthew D., Goedken, Michael J., Snyder, Shane A., Cherrington, Nathan J.
Publicado no Toxicol Sci (2014)