Basolateral Uptake of Nucleosides by Sertoli Cells Is Mediated Primarily by Equilibrative Nucleoside Transporter 1

The blood-testis barrier (BTB) prevents the entry of many xenobiotic compounds into seminiferous tubules thereby protecting developing germ cells. Understanding drug transport across the BTB may improve drug delivery into the testis. Members of one class of drug, nucleoside reverse transcriptase inh...

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Detalhes bibliográficos
Main Authors: Klein, David M., Evans, Kristen K., Hardwick, Rhiannon N., Dantzler, William H., Wright, Stephen H., Cherrington, Nathan J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Metabolism, Transport, and Pharmacogenomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684844/
https://ncbi.nlm.nih.gov/pubmed/23639800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.203265
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