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The Role of Nucleoside Transporters in the Erythrocyte Disposition and Oral Absorption of Ribavirin in the Wild-Type and Equilibrative Nucleoside Transporter 1(−/−) Mice

Ribavirin [1-(β-d-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide] is the treatment of choice for hepatitis C virus infection. Ribavirin is a substrate of several nucleoside transporters, including the equilibrative nucleoside transporter (Ent) and the concentrative nucleoside transporter 2. To deter...

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Detalhes bibliográficos
Main Authors: Endres, Christopher J., Moss, Aaron M., Govindarajan, Rajgopal, Choi, Doo-Sup, Unadkat, Jashvant D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766233/
https://ncbi.nlm.nih.gov/pubmed/19602549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.153130
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