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The Role of the Equilibrative Nucleoside Transporter 1 on Tissue and Fetal Distribution of Ribavirin in the Mouse

Ribavirin is used for the treatment of hepatitis C virus (HCV) infection. The equilibrative nucleoside transporter 1 (ENT1) expressed in hepatocytes transports ribavirin into the liver, the site of efficacy of the drug. However, it is still unclear whether ENT1 plays a dominant role in the hepatic d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biopharm Drug Dispos
Hauptverfasser: Endres, Christopher J., Moss, Aaron M., Ishida, Kazuya, Govindarajan, Rajgopal, Unadkat, Jashvant D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120975/
https://ncbi.nlm.nih.gov/pubmed/27194214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.2015
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