P-glycoprotein-Based Loperamide-Cyclosporine Drug Interaction at the Rat Blood-Brain Barrier: Prediction from In Vitro Studies and Extrapolation to Humans

door Hsiao, Peng, Unadkat, Jashvant D.
Gepubliceerd in 2012

Interaction between HIV Protease Inhibitors (PIs) and Hepatic Transporters in Sandwich Cultured Human Hepatocytes: Implication for PI-based DDIs

door Liu, Li, Unadkat, Jashvant D.
Gepubliceerd in 2013

Comparison of Heavy Labeled (SIL) Peptide versus SILAC Protein Internal Standards for LC-MS/MS Quantification of Hepatic Drug Transporters

door Prasad, Bhagwat, Unadkat, Jashvant D.
Gepubliceerd in 2014

Predicting the Outer Boundaries of P-glycoprotein (P-gp)-Based Drug Interactions at the Human Blood-Brain Barrier Based on Rat Studies

door Hsiao, Peng, Unadkat, Jashvant D
Gepubliceerd in 2014

Optimized Approaches for Quantification of Drug Transporters in Tissues and Cells by MRM Proteomics

door Prasad, Bhagwat, Unadkat, Jashvant D.
Gepubliceerd in 2014

Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in Drug Transport—an Update

door Mao, Qingcheng, Unadkat, Jashvant D.
Gepubliceerd in AAPS J (2014)

Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model II: Verification of the model for passive placental permeability drugs

door Zhang, Zufei, Unadkat, Jashvant D.
Gepubliceerd in Drug Metab Dispos (2017)

Impact of Ignoring Extraction Ratio When Predicting Drug-Drug Interactions, Fraction Metabolized, and Intestinal First-Pass Contribution

door Kirby, Brian J., Unadkat, Jashvant D.
Gepubliceerd in 2010

Transport vs. metabolism: what determines the pharmacokinetics (PK) and pharmacodynamics (PD) of drugs? Insights from the extended clearance model

door Patilea-Vrana, Gabriela, Unadkat, Jashvant D.
Gepubliceerd in Clin Pharmacol Ther (2016)

Drug interactions at the blood-brain barrier: fact or fantasy?

door Eyal, Sara, Hsiao, Peng, Unadkat, Jashvant D.
Gepubliceerd in 2009

Hormonal Regulation of BCRP Expression in Human Placental BeWo Cells

door Wang, Honggang, Unadkat, Jashvant D., Mao, Qingcheng
Gepubliceerd in 2007

When Does the Rate-Determining Step in the Hepatic Clearance of a Drug Switch from Sinusoidal Uptake to All Hepatobiliary Clearances? Implications for Predicting Drug-Drug Interact...

door Patilea-Vrana, Gabriela I., Unadkat, Jashvant D.
Gepubliceerd in Drug Metab Dispos (2018)

Quantifying Hepatic Enzyme Kinetics of (-)-∆(9)-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC, through In Vitro Modeling

door Patilea-Vrana, Gabriela I., Unadkat, Jashvant D.
Gepubliceerd in Drug Metab Dispos (2019)

Development and Verification of a Linked Δ(9)-THC/11-OH-THC Physiologically Based Pharmacokinetic Model in Healthy, Nonpregnant Population and Extrapolation to Pregnant Women

door Patilea-Vrana, Gabriela I., Unadkat, Jashvant D.
Gepubliceerd in Drug Metab Dispos (2021)

CYP2D6 Is Inducible by Endogenous and Exogenous Corticosteroids

door Farooq, Muhammad, Kelly, Edward J., Unadkat, Jashvant D.
Gepubliceerd in Drug Metab Dispos (2016)

Mechanisms of CYP3A induction during pregnancy: studies in HepaRG cells

door Sachar, Madhav, Kelly, Edward J., Unadkat, Jashvant D.
Gepubliceerd in AAPS J (2019)

Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative n...

door Endres, Christopher J, Sengupta, Dhruba J, Unadkat, Jashvant D
Gepubliceerd in 2004

Effect of Pregnancy on Nitrofurantoin Disposition in Mice

door ZHANG, YI, ZHOU, LIN, UNADKAT, JASHVANT D., MAO, QINGCHENG
Gepubliceerd in 2009

Interplay of Drug Metabolism and Transport: A Real Phenomenon or an Artifact of the Site of Measurement?

door Endres, Christopher J., Endres, Michael G., Unadkat, Jashvant D.
Gepubliceerd in 2009

Hepatic Enzymes Relevant to the Disposition of (−)-∆(9)-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC

door Patilea-Vrana, Gabriela I., Anoshchenko, Olena, Unadkat, Jashvant D.
Gepubliceerd in Drug Metab Dispos (2019)