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Interplay of Drug Metabolism and Transport: A Real Phenomenon or an Artifact of the Site of Measurement?

The interdependence of both transport and metabolism on the disposition of drugs has recently gained heightened attention in the literature, and has been termed the “interplay of transport and metabolism”. Such “interplay” is observed when inhibition of biliary clearance of a drug results in an “app...

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Detalhes bibliográficos
Main Authors: Endres, Christopher J., Endres, Michael G., Unadkat, Jashvant D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801584/
https://ncbi.nlm.nih.gov/pubmed/19886641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp9002392
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