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The Drug Transporter-Metabolism Alliance: Uncovering and Defining the Interplay
Two decades ago the importance of transporter-enzyme interplay and its effects on drug bioavailability and hepatic disposition were first recognized. Here we review the history of uncovering and defining this interplay with a primary emphasis on studies from our laboratory. We review the early 1990s...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796475/ https://ncbi.nlm.nih.gov/pubmed/19874004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900253n |
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