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The Drug Transporter-Metabolism Alliance: Uncovering and Defining the Interplay

Two decades ago the importance of transporter-enzyme interplay and its effects on drug bioavailability and hepatic disposition were first recognized. Here we review the history of uncovering and defining this interplay with a primary emphasis on studies from our laboratory. We review the early 1990s...

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Detalhes bibliográficos
Autor principal: Benet, Leslie Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796475/
https://ncbi.nlm.nih.gov/pubmed/19874004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900253n
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