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PREDICTING DRUG DISPOSITION, ABSORPTION / ELIMINATION / TRANSPORTER INTERPLAY AND THE ROLE OF FOOD ON DRUG ABSORPTION

The ability to predict drug disposition involves concurrent consideration of many chemical and physiological variables and the effect of food on the rate and extent of availability adds further complexity due to postprandial changes in the gastrointestinal (GI) tract. A system that allows for the as...

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Détails bibliographiques
Auteurs principaux: Custodio, Joseph M., Wu, Chi-Yuan, Benet, Leslie Z.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292816/
https://ncbi.nlm.nih.gov/pubmed/18199522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2007.08.043
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