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The Drug Transporter-Metabolism Alliance: Uncovering and Defining the Interplay

Two decades ago the importance of transporter-enzyme interplay and its effects on drug bioavailability and hepatic disposition were first recognized. Here we review the history of uncovering and defining this interplay with a primary emphasis on studies from our laboratory. We review the early 1990s...

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Bibliographic Details
Main Author: Benet, Leslie Z.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796475/
https://ncbi.nlm.nih.gov/pubmed/19874004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900253n
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