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The Role of Transporters in the Pharmacokinetics of Orally Administered Drugs

Drug transporters are recognized as key players in the processes of drug absorption, distribution, metabolism, and elimination. The localization of uptake and efflux transporters in organs responsible for drug biotransformation and excretion gives transporter proteins a unique gatekeeper function in...

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Detalhes bibliográficos
Main Authors: Shugarts, Sarah, Benet, Leslie Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719753/
https://ncbi.nlm.nih.gov/pubmed/19568696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9924-0
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