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Effects of Drug Transporters on Volume of Distribution

Recently, drug transporters have emerged as significant modifiers of a patient’s pharmacokinetics. In cases where the functioning of drug transporters is altered, such as by drug-drug interactions, by genetic polymorphisms, or as evidenced in knockout animals, the resulting change in volume of distr...

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Detalhes bibliográficos
Main Authors: Grover, Anita, Benet, Leslie Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691462/
https://ncbi.nlm.nih.gov/pubmed/19399628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9102-7
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