Transport vs. metabolism: what determines the pharmacokinetics (PK) and pharmacodynamics (PD) of drugs? Insights from the extended clearance model

Míreanna Comhchosúla

• When Does the Rate-Determining Step in the Hepatic Clearance of a Drug Switch from Sinusoidal Uptake to All Hepatobiliary Clearances? Implications for Predicting Drug-Drug Interactions
  le: Patilea-Vrana, Gabriela I., et al.
  Foilsithe: (2018)
• Development and Verification of a Linked Δ(9)-THC/11-OH-THC Physiologically Based Pharmacokinetic Model in Healthy, Nonpregnant Population and Extrapolation to Pregnant Women
  le: Patilea-Vrana, Gabriela I., et al.
  Foilsithe: (2021)
• Pharmacokinetics (PK), Pharmacodynamics (PD), and PK-PD Integration of Danofloxacin in Sheep Biological Fluids
  le: Aliabadi, F. Shojaee, et al.
  Foilsithe: (2003)
• In vitro dynamic pharmacokinetic/pharmacodynamic(PK/PD) modeling and PK/PD cutoff of cefquinome against Haemophilus parasuis
  le: Xiao, Xia, et al.
  Foilsithe: (2015)
• 1321. Population Pharmacokinetic (PK) and Pharmacokinetic/Pharmacodynamic (PK/PD) Target Attainment Analyses for Dalbavancin in Pediatric Patients
  le: Carrothers, Timothy J, et al.
  Foilsithe: (2020)