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CYP2D6 Is Inducible by Endogenous and Exogenous Corticosteroids
Although cytochrome P450 (CYP) 2D6 has been widely considered to be noninducible on the basis of human hepatocyte studies, in vivo data suggests that it is inducible by endo- and xenobiotics. Therefore, we investigated if the experimental conditions routinely used in human hepatocyte studies may be...
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| Publicado no: | Drug Metab Dispos |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4851303/ https://ncbi.nlm.nih.gov/pubmed/26965986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.069229 |
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