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CYP2D6 Is Inducible by Endogenous and Exogenous Corticosteroids
Although cytochrome P450 (CYP) 2D6 has been widely considered to be noninducible on the basis of human hepatocyte studies, in vivo data suggests that it is inducible by endo- and xenobiotics. Therefore, we investigated if the experimental conditions routinely used in human hepatocyte studies may be...
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| Pubblicato in: | Drug Metab Dispos |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4851303/ https://ncbi.nlm.nih.gov/pubmed/26965986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.069229 |
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