Functional expression of the Wilson disease protein reveals mislocalization and impaired copper-dependent trafficking of the common H1069Q mutation

Por Payne, Aimee S., Kelly, Edward J., Gitlin, Jonathan D.
Publicado em 1998

Expression and Characterization of CYP4V2 as a Fatty Acid ω-Hydroxylase

Por Nakano, Mariko, Kelly, Edward J., Rettie, Allan E.
Publicado em 2009

CYP2D6 Is Inducible by Endogenous and Exogenous Corticosteroids

Por Farooq, Muhammad, Kelly, Edward J., Unadkat, Jashvant D.
Publicado no Drug Metab Dispos (2016)

Concise Review: Current and Emerging Biomarkers of Nephrotoxicity

Por Weber, Elijah J, Himmelfarb, Jonathan, Kelly, Edward J
Publicado no Curr Opin Toxicol (2017)

Development and characterization of transgenic mouse models for conditional gene knockout in the blood–brain and blood-CSF barriers

Por Crouthamel, Matthew H., Kelly, Edward J., Ho, Rodney J. Y.
Publicado em 2011

Generation and Characterization of a Cyp4b1 Null Mouse and the Role of CYP4B1 in the Activation and Toxicity of Ipomeanol

Por Parkinson, Oliver T., Liggitt, H. Denny, Rettie, Allan E., Kelly, Edward J.
Publicado em 2013

Generation and Characterization of a Murine Model of Bietti Crystalline Dystrophy

Por Lockhart, Catherine M., Nakano, Mariko, Rettie, Allan E., Kelly, Edward J.
Publicado em 2014

Ocular cytochrome P450s and transporters: roles in disease and endobiotic and xenobiotic disposition

Por Nakano, Mariko, Lockhart, Catherine M., Kelly, Edward J., Rettie, Allan E.
Publicado no Drug Metab Rev (2014)

A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes

Por Kelly, Edward J., Sandgren, Eric P., Brinster, Ralph L., Palmiter, Richard D.
Publicado em 1997

CYP4V2 in Bietti's Crystalline Dystrophy: Ocular Localization, Metabolism of ω-3-Polyunsaturated Fatty Acids, and Functional Deficit of the p.H331P Variant

Por Nakano, Mariko, Kelly, Edward J., Wiek, Constanze, Hanenberg, Helmut, Rettie, Allan E.
Publicado em 2012

Bioactivation of 4-Ipomeanol by a CYP4B Enzyme in Bovine Lung and Inhibition by HET0016

Por Parkinson, Oliver T., Kelly, Edward J., Bezabih, Efriem, Whittington, Dale, Rettie, Allan E.
Publicado em 2011

Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics

Por Bajaj, Piyush, Chowdhury, Swapan K., Yucha, Robert, Kelly, Edward J., Xiao, Guangqing
Publicado no Drug Metab Dispos (2018)

Finding Homes for Orphan Cytochrome P450s: CYP4V2 and CYP4F22 in Disease States

Por Kelly, Edward J., Nakano, Mariko, Rohatgi, Priyanka, Yarov-Yarovoy, Vladimir, Rettie, Allan E.
Publicado em 2011

Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity

Por Parkinson, Oliver T., Teitelbaum, Aaron M., Whittington, Dale, Kelly, Edward J., Rettie, Allan E.
Publicado no Drug Metab Dispos (2016)

Transcriptomic profiling of PBDE-exposed HepaRG cells unveils critical lncRNA- PCG pairs involved in intermediary metabolism

Por Zhang, Angela, Li, Cindy Yanfei, Kelly, Edward J., Sheppard, Lianne, Cui, Julia Yue
Publicado no PLoS One (2020)

Protein tyrosine nitration of mitochondrial carbamoyl phosphate synthetase 1 and its functional consequences

Por Takakusa, Hideo, Mohar, Isaac, Kavanagh, Terrance J., Kelly, Edward J., Kaspera, Rüdiger, Nelson, Sidney D.
Publicado em 2012

Translational Assessment of Drug‐Induced Proximal Tubule Injury Using a Kidney Microphysiological System

Por Maass, Christian, Sorensen, Nathan B., Himmelfarb, Jonathan, Kelly, Edward J., Stokes, Cynthia L., Cirit, Murat
Publicado no CPT Pharmacometrics Syst Pharmacol (2019)

Tissue Chips in Space—Challenges and Opportunities

Por Yeung, Catherine K., Koenig, Paul, Countryman, Stefanie, Thummel, Kenneth E., Himmelfarb, Jonathan, Kelly, Edward J.
Publicado no Clin Transl Sci (2019)

Novel cytochrome P450-2D6 promoter sequence variations in hepatitis C positive and negative subjects()

Por Ho, Martin T., Kelly, Edward J., Bodor, Miklos, Bui, Tot, Kowdley, Kris V., Ho, Rodney J.Y.
Publicado em 2011

Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function

Por Chang, Shih-Yu, Weber, Elijah J., Van Ness, Kirk P., Eaton, David L., Kelly, Edward J.
Publicado no Clin Pharmacol Ther (2016)