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Generation and Characterization of a Murine Model of Bietti Crystalline Dystrophy

PURPOSE. Bietti crystalline dystrophy (BCD) is a rare, autosomal recessive, progressive, degenerative eye disease caused by mutations in the CYP4V2 gene, for which no treatments are currently available. Cyp4v3 is the murine ortholog to CYP4V2, and to better understand the molecular pathogenesis of t...

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Detalhes bibliográficos
Main Authors: Lockhart, Catherine M., Nakano, Mariko, Rettie, Allan E., Kelly, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160072/
https://ncbi.nlm.nih.gov/pubmed/25118264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13717
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