The effect of quinidine, used as a probe for the involvement of P-glycoprotein, on the intestinal absorption and pharmacodynamics of methadone

Por Kharasch, Evan D, Hoffer, Christine, Whittington, Dale
Publicado em 2004

Evaluating Investments in Typhoid Vaccines in Two Slums in Kolkata, India

Por Cook, Joseph, Sur, Dipika, Clemens, John, Whittington, Dale
Publicado em 2009

Simultaneous Measurement of Etravirine, Maraviroc and Raltegravir in Pigtail Macaque Plasma, Vaginal Secretions and Vaginal Tissue using a LC-MS/MS Assay

Por Blakney, Anna K., Jiang, Yonghou, Whittington, Dale, Woodrow, Kim A.
Publicado no J Chromatogr B Analyt Technol Biomed Life Sci (2016)

Methadone Pharmacokinetics are Independent of Cytochrome P4503A (CYP3A) Activity and Gastrointestinal Drug Transport: Insights from Methadone Interactions with Ritonavir/Indinavir

Por Kharasch, Evan D., Hoffer, Christine, Whittington, Dale, Walker, Alysa, Bedynek, Pamela Sheffels
Publicado em 2009

Bioactivation of 4-Ipomeanol by a CYP4B Enzyme in Bovine Lung and Inhibition by HET0016

Por Parkinson, Oliver T., Kelly, Edward J., Bezabih, Efriem, Whittington, Dale, Rettie, Allan E.
Publicado em 2011

Lack of Indinavir Effects on Methadone Disposition Despite Inhibition of Hepatic and Intestinal Cytochrome P4503A (CYP3A)

Por Kharasch, Evan D., Bedynek, Pamela Sheffels, Hoffer, Christine, Walker, Alysa, Whittington, Dale
Publicado em 2012

Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity

Por Kharasch, Evan D., Walker, Alysa, Whittington, Dale, Hoffer, Christine, Bedynek, Pamela Sheffels
Publicado em 2009

The Long-Term Dynamics of Mortality Benefits from Improved Water and Sanitation in Less Developed Countries

Por Jeuland, Marc A., Fuente, David E., Ozdemir, Semra, Allaire, Maura C., Whittington, Dale
Publicado em 2013

PhoPQ regulates acidic glycerophospholipid content of the Salmonella Typhimurium outer membrane

Por Dalebroux, Zachary D., Matamouros, Susana, Whittington, Dale, Bishop, Russell E., Miller, Samuel I.
Publicado em 2014

Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity

Por Parkinson, Oliver T., Teitelbaum, Aaron M., Whittington, Dale, Kelly, Edward J., Rettie, Allan E.
Publicado no Drug Metab Dispos (2016)

Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics. II. Ritonavir effects on CYP3A and P-glycoprotein activities

Por Kharasch, Evan D., Bedynek, Pamela Sheffels, Walker, Alysa, Whittington, Dale, Hoffer, Christine, Park, Sang
Publicado em 2008

Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics I. Evidence against CYP3A mediation of methadone clearance

Por Kharasch, Evan D., Bedynek, Pamela Sheffels, Park, Sang, Whittington, Dale, Walker, Alysa, Hoffer, Christine
Publicado em 2008

As in Humans, Pregnancy Increases the Clearance of the Protease Inhibitor Nelfinavir in the Nonhuman Primate Macaca nemestrina

Por Zhang, Huixia, Wu, Xiaohui, Chung, Francisco, Naraharisetti, Suresh Babu, Whittington, Dale, Mirfazaelian, Ahmad, Unadkat, Jashvant D.
Publicado em 2009

Pregnancy Does Not Increase CYP3A or P-Glycoprotein Activity in the Non-Human Primate, Macaca nemestrina

Por Zhang, Huixia, Wu, Xiaohui, Naraharisetti, Suresh Babu, Chung, Francisco, Whittington, Dale, Mirfazaelian, Ahmad, Unadkat, Jashvant D.
Publicado em 2009

Tuning a High Transmission Ion Guide to Prevent Gas-Phase Proton Exchange During H/D Exchange MS Analysis

Por Guttman, Miklos, Wales, Thomas E., Whittington, Dale, Engen, John R., Brown, Jeffery M., Lee, Kelly K.
Publicado no J Am Soc Mass Spectrom (2016)

Glutathione transferase A4-4 resists adduction by 4-hydroxynonenal

Por Shireman, Laura M., Kripps, Kimberly A., Balogh, Larissa M., Conner, Kip P., Whittington, Dale, Atkins, William M.
Publicado em 2010

Complex Drug Interactions of HIV Protease Inhibitors 1: Inactivation, Induction, and Inhibition of Cytochrome P450 3A by Ritonavir or Nelfinavir

Por Kirby, Brian J., Collier, Ann C., Kharasch, Evan D., Whittington, Dale, Thummel, Kenneth E., Unadkat, Jashvant D.
Publicado em 2011

Complex Drug Interactions of the HIV Protease Inhibitors 3: Effect of Simultaneous or Staggered Dosing of Digoxin and Ritonavir, Nelfinavir, Rifampin, or Bupropion

Por Kirby, Brian J., Collier, Ann C., Kharasch, Evan D., Whittington, Dale, Thummel, Kenneth E., Unadkat, Jashvant D.
Publicado em 2012

Fatty-acyl chain profiles of cellular phosphoinositides

Por Traynor-Kaplan, Alexis, Kruse, Martin, Dickson, Eamonn J., Dai, Gucan, Vivas, Oscar, Yu, Haijie, Whittington, Dale, Hille, Bertil
Publicado no Biochim Biophys Acta (2017)

Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes

Por Govindarajan, Rajgopal, Endres, Christopher J., Whittington, Dale, LeCluyse, Edward, Pastor-Anglada, Marçal, Tse, Chung-Ming, Unadkat, Jashvant D.
Publicado em 2008