In vitro models for liver toxicity testing

Por Soldatow, Valerie Y., LeCluyse, Edward L., Griffith, Linda G., Rusyn, Ivan
Publicado em 2012

Organotypic liver culture models: Meeting current challenges in toxicity testing

Por LeCluyse, Edward L., Witek, Rafal P., Andersen, Melvin E., Powers, Mark J.
Publicado em 2012

Subtoxic Alterations in Hepatocyte-Derived Exosomes: An Early Step in Drug-Induced Liver Injury?

Por Holman, Natalie S., Mosedale, Merrie, Wolf, Kristina K., LeCluyse, Edward L., Watkins, Paul B.
Publicado no Toxicol Sci (2016)

Co-culture of Hepatocytes and Kupffer Cells as an In Vitro Model of Inflammation and Drug-Induced Hepatotoxicity

Por Rose, Kelly A., Holman, Natalie S., Green, Angela M., Andersen, Melvin E., LeCluyse, Edward L.
Publicado no J Pharm Sci (2016)

Editor’s Highlight: Modeling Compound-Induced Fibrogenesis In Vitro Using Three-Dimensional Bioprinted Human Liver Tissues

Por Norona, Leah M., Nguyen, Deborah G., Gerber, David A., Presnell, Sharon C., LeCluyse, Edward L.
Publicado no Toxicol Sci (2016)

Early Identification of Clinically Relevant Drug Interactions With the Human Bile Salt Export Pump (BSEP/ABCB11)

Por Pedersen, Jenny M., Matsson, Pär, Bergström, Christel A. S., Hoogstraate, Janet, Norén, Agneta, LeCluyse, Edward L., Artursson, Per
Publicado em 2013

Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes

Por Govindarajan, Rajgopal, Endres, Christopher J., Whittington, Dale, LeCluyse, Edward, Pastor-Anglada, Marçal, Tse, Chung-Ming, Unadkat, Jashvant D.
Publicado em 2008

Relative Activation of Human Pregnane X Receptor versus Constitutive Androstane Receptor Defines Distinct Classes of CYP2B6 and CYP3A4 Inducers

Por Faucette, Stephanie R., Zhang, Tong-Cun, Moore, Rick, Sueyoshi, Tatsuya, Omiecinski, Curtis J., LeCluyse, Edward L., Negishi, Masahiko, Wang, Hongbing
Publicado em 2006

EVALUATION OF AN IN VITRO TOXICOGENETIC MOUSE MODEL FOR HEPATOTOXICITY

Por Martinez, Stephanie M., Bradford, Blair U., Soldatow, Valerie Y., Kosyk, Oksana, Sandot, Amelia, Witek, Rafal, Kaiser, Robert, Stewart, Todd, Amaral, Kirsten, Freeman, Kimberly, Black, Chris, LeCluyse, Edward L., Ferguson, Stephen S., Rusyn, Ivan
Publicado em 2010

Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing

Por Wetmore, Barbara A., Wambaugh, John F., Allen, Brittany, Ferguson, Stephen S., Sochaski, Mark A., Setzer, R. Woodrow, Houck, Keith A., Strope, Cory L., Cantwell, Katherine, Judson, Richard S., LeCluyse, Edward, Clewell, Harvey J., Thomas, Russell S., Andersen, Melvin E.
Publicado no Toxicol Sci (2015)

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of...

Por Godoy, Patricio, Hewitt, Nicola J., Albrecht, Ute, Andersen, Melvin E., Ansari, Nariman, Bhattacharya, Sudin, Bode, Johannes Georg, Bolleyn, Jennifer, Borner, Christoph, Böttger, Jan, Braeuning, Albert, Budinsky, Robert A., Burkhardt, Britta, Cameron, Neil R., Camussi, Giovanni, Cho, Chong-Su, Choi, Yun-Jaie, Craig Rowlands, J., Dahmen, Uta, Damm, Georg, Dirsch, Olaf, Donato, María Teresa, Dong, Jian, Dooley, Steven, Drasdo, Dirk, Eakins, Rowena, Ferreira, Karine Sá, Fonsato, Valentina, Fraczek, Joanna, Gebhardt, Rolf, Gibson, Andrew, Glanemann, Matthias, Goldring, Chris E. P., Gómez-Lechón, María José, Groothuis, Geny M. M., Gustavsson, Lena, Guyot, Christelle, Hallifax, David, Hammad, Seddik, Hayward, Adam, Häussinger, Dieter, Hellerbrand, Claus, Hewitt, Philip, Hoehme, Stefan, Holzhütter, Hermann-Georg, Houston, J. Brian, Hrach, Jens, Ito, Kiyomi, Jaeschke, Hartmut, Keitel, Verena, Kelm, Jens M., Kevin Park, B., Kordes, Claus, Kullak-Ublick, Gerd A., LeCluyse, Edward L., Lu, Peng, Luebke-Wheeler, Jennifer, Lutz, Anna, Maltman, Daniel J., Matz-Soja, Madlen, McMullen, Patrick, Merfort, Irmgard, Messner, Simon, Meyer, Christoph, Mwinyi, Jessica, Naisbitt, Dean J., Nussler, Andreas K., Olinga, Peter, Pampaloni, Francesco, Pi, Jingbo, Pluta, Linda, Przyborski, Stefan A., Ramachandran, Anup, Rogiers, Vera, Rowe, Cliff, Schelcher, Celine, Schmich, Kathrin, Schwarz, Michael, Singh, Bijay, Stelzer, Ernst H. K., Stieger, Bruno, Stöber, Regina, Sugiyama, Yuichi, Tetta, Ciro, Thasler, Wolfgang E., Vanhaecke, Tamara, Vinken, Mathieu, Weiss, Thomas S., Widera, Agata, Woods, Courtney G., Xu, Jinghai James, Yarborough, Kathy M., Hengstler, Jan G.
Publicado em 2013