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In vitro models for liver toxicity testing

Over the years, various liver-derived in vitro model systems have been developed to enable investigation of the potential adverse effects of chemicals and drugs. Liver tissue slices, isolated microsomes, perfused liver, immortalized cell lines, and primary hepatocytes have been used extensively. Imm...

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Autors principals: Soldatow, Valerie Y., LeCluyse, Edward L., Griffith, Linda G., Rusyn, Ivan
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593300/
https://ncbi.nlm.nih.gov/pubmed/23495363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2TX20051A
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